Effectiveness of oral electrolyte solutions with different compositions for the treatment of neonatal calves with induced osmotic diarrhea

ABSTRACT In a randomized controlled trial, we evaluated the effects of five oral electrolyte solutions (OESs) with different compositions water, electrolyte, and acid-base balances diarrheal neonatal calves. Osmotic diarrhea dehydration were induced sucrose in milk, spironolactone, hydrochlorothiazide for 48 h thirty 10-day old Holstein healthy calves 43.5 ± 3.80 kg BW who fed natural milk. They allocated to treatment groups (n=6) based on administered OES (commercial: A, B, C, D; non-commercial: UEL). On day treatment, received 6L two doses apart from milk intakes. Venous blood samples collected at -48h (start induction), -24h, 0h day), 8h, 16h, 24h, 48h, 72h. TPP, glucose, D-lactate, L-lactate, pH, pCO2, HCO3 -, BE, Na+, K+, Cl-, SID3, SIG, AG, Atot percentage change plasma volume (%PV) measured or calculated analyzed by two-way repeated measures ANOVA. All developed osmotic diarrhea, mild moderate dehydration, hyponatremia, relative hyperchloremia, severe metabolic acidosis. The tested OESs well accepted effective reversing imbalances, D did not completely correct SEO B caused transient hyperglycemia. It has been concluded that all are safe degrees acidosis, which indicates they have proper this purpose.